Endocrine Abstracts

: Nonfunctioning pituitary adenomas (NPA) are prevalent neoplams from pituitary. The best treatment is the surgical approach but residual tumours are common. For residual tumours the options are radiotherapy (RT) and re-surgery. There are no significant studies testing drugs in NPA. Due to the fact that these tumors express dopamine D2 receptors, dopamine agonists that may be useful in patients with NPA.Methods: We selected 145 patients with residual tum...

Considered as the biggest public health problem, the pandemic growth of obesity is associated to decline of male fertility potential over the last 50 years. Thus far, the effect of weight loss on semen parameters is still controversial and poorly understood. In this study we report the effect of significant weight loss on semen parameters of two obese men with metabolic syndrome. The patients followed to a very low-calorie ketogenic diet (VLCKD) according to a commercial weigh...

Obesity is the single most significant risk factor for testosterone deficiency in men, with a reported prevalence up of 60% of male obesity secondary hypogonadism (MOSH). Several studies have shown that significant weight loss due to bariatric surgery have significant metabolic and endocrine improvement in obesity, however the results achieved with conventional diet and lifestyle change are poor and not able to reverse this condition. As an alternative to bariatric surgery, we...